November 20th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 56 | Shelly Hutson | 1173 | 44 | F | 57:45.1 | 9:19/M | 1:F 40-44 | |
| 57 | Crystal Barksdale | 1077 | 44 | F | Roanoke VA | 57:48.6 | 9:19/M | 2:F 40-44 |
| 60 | Christine Mortlock | 1181 | 41 | F | Roanoke VA | 58:53.7 | 9:30/M | 3:F 40-44 |
| 68 | Sabra Robitaille | 1052 | 40 | F | Roanoke VA | 59:41.9 | 9:38/M | 4:F 40-44 |
| 70 | Jamie Capaldo | 1060 | 42 | F | 1:00:04.3 | 9:41/M | 5:F 40-44 | |
| 74 | Rebekah McGeorge | 1160 | 42 | F | Vinton VA | 1:00:15.5 | 9:43/M | 6:F 40-44 |
| 88 | Brittny McGraw | 1171 | 40 | F | Roanoke VA | 1:02:11.6 | 10:02/M | 7:F 40-44 |
| 89 | Rebecca Eichelberger | 1029 | 42 | F | Glasgow VA | 1:02:14.2 | 10:02/M | 8:F 40-44 |
| 107 | Ashley Engels | 1103 | 42 | F | 1:06:23.3 | 10:42/M | 9:F 40-44 | |
| 111 | Carrie Turnbull | 1100 | 43 | F | 1:06:54.2 | 10:47/M | 10:F 40-44 | |
| 112 | Emily Cohen | 1183 | 41 | F | Roanoke VA | 1:06:54.3 | 10:47/M | 11:F 40-44 |
| 125 | Karen Bledsoe | 1039 | 44 | F | Raleigh NC | 1:13:15.8 | 11:49/M | 12:F 40-44 |
| 131 | Michelle Dowdy | 1082 | 40 | F | Lynchburg VA | 1:15:02.8 | 12:06/M | 13:F 40-44 |
| 138 | Jordan Tucker | 1022 | 40 | F | Roanoke | 1:23:24.8 | 13:27/M | 14:F 40-44 |
| 140 | Kitty Walls | 1115 | 42 | F | Hardy VA | 1:24:57.0 | 13:42/M | 15:F 40-44 |
| 148 | Stephanie Spiller | 1058 | 44 | F | Roanoke VA | 1:33:47.7 | 15:08/M | 16:F 40-44 |