October 2nd, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 20 | Elizabeth Schenkel | 793 | 45 | F | Moneta VA | 26:51.3 | 8:40/M | 1:F 40-49 |
| 24 | Adrien Monti | 774 | 42 | F | Roanoke VA | 27:06.3 | 8:45/M | 2:F 40-49 |
| 26 | Kathryn Mustard | 776 | 46 | F | Roanoke VA | 27:09.9 | 8:46/M | 3:F 40-49 |
| 28 | Corinne Noirot | 777 | 45 | F | Troutville VA | 27:11.7 | 8:46/M | 4:F 40-49 |
| 32 | Erin Morris | 775 | 45 | F | Roanoke VA | 28:15.6 | 9:07/M | 5:F 40-49 |
| 33 | Jodi Judge | 756 | 44 | F | Roanoke VA | 28:31.5 | 9:12/M | 6:F 40-49 |
| 35 | Jean Hazelwood | 748 | 45 | F | Sweet Briar VA | 29:28.1 | 9:30/M | 7:F 40-49 |
| 41 | Beverly Pitzer | 782 | 47 | F | 30:05.1 | 9:42/M | 8:F 40-49 | |
| 60 | Heather Quesinberry | 829 | 41 | F | Roanoke VA | 33:00.0 | 10:39/M | 9:F 40-49 |
| 63 | Heba Gebrael | 740 | 44 | F | Roanoke VA | 33:04.5 | 10:40/M | 10:F 40-49 |
| 68 | Mona Raza | 785 | 48 | F | Roanoke VA | 34:55.0 | 11:16/M | 11:F 40-49 |
| 71 | Virginia Pannabecker | 781 | 44 | F | Blacksburg VA | 35:37.6 | 11:30/M | 12:F 40-49 |
| 76 | Melissa Michalski | 771 | 48 | F | 37:06.2 | 11:58/M | 13:F 40-49 | |
| 82 | Jessica Delgado | 770 | 46 | F | Troutville VA | 39:47.3 | 12:50/M | 14:F 40-49 |
| 88 | Sarah Young | 825 | 43 | F | Roanoke VA | 43:19.0 | 13:58/M | 15:F 40-49 |
| 93 | Allison Weiss | 816 | 45 | F | Blue Ridge VA | 47:16.8 | 15:15/M | 16:F 40-49 |
| 94 | Courtney Treece | 812 | 44 | F | Buchanan VA | 53:29.8 | 17:15/M | 17:F 40-49 |