September 4th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 27 | Natalie Daniel | 323 | 44 | F | Mount Holly NC | 5:49:07.1 | 11:38/M | 1:F 40-44 |
| 48 | Jennifer Nelson | 361 | 40 | F | Blacksburg VA | 6:43:03.8 | 13:26/M | 2:F 40-44 |
| 52 | Chelsie Viar | 392 | 41 | F | Lynchburg VA | 6:55:46.9 | 13:52/M | 3:F 40-44 |
| 55 | Leslie Smith | 381 | 43 | F | Johnson City TN | 7:02:11.9 | 14:04/M | 4:F 40-44 |
| 61 | Elizabeth Johnson | 348 | 40 | F | Roanoke VA | 7:32:12.6 | 15:04/M | 5:F 40-44 |
| 70 | Ercilia Ward | 4027 | 41 | F | Roanoke VA | 7:47:17.4 | 15:35/M | 6:F 40-44 |
| 75 | Stacy Saunders | 376 | 42 | F | Ashland KY | 8:11:41.6 | 16:23/M | 7:F 40-44 |
| 78 | Emily Clymer | 313 | 41 | F | Cincinnati OH | 8:15:45.3 | 16:32/M | 8:F 40-44 |