September 4th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 20 | Kimberly Psaltis | 197 | 47 | F | Chapel Hill NC | 2:57:06.6 | 11:04/M | 1:F 45-49 |
| 49 | Kim Stewart | 216 | 49 | F | Norfolk VA | 3:26:39.4 | 12:55/M | 2:F 45-49 |
| 55 | Tabitha King | 165 | 47 | F | Bedford VA | 3:31:58.3 | 13:15/M | 3:F 45-49 |
| 62 | Tabitha Walker | 233 | 48 | F | Hardy VA | 3:40:41.9 | 13:48/M | 4:F 45-49 |
| 64 | Carin Smith | 213 | 46 | F | Bakersville NC | 3:41:41.8 | 13:51/M | 5:F 45-49 |
| 91 | Sandy Jones | 163 | 45 | F | Galax VA | 4:04:38.7 | 15:17/M | 6:F 45-49 |
| 108 | Tracy James | 159 | 46 | F | Boones Mill VA | 4:48:40.1 | 18:03/M | 7:F 45-49 |
| 110 | Shawna Bryce | 113 | 47 | F | Mars Hill NC | 5:06:19.6 | 19:09/M | 8:F 45-49 |