May 7th, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 45 | Jenna Cleveland | 678 | 39 | F | Blacksburg VA | 2:16:47.30 | 10:15/M | 1:F 35-39 |
| 49 | Heather Stokes | 601 | 38 | F | Roanoke VA | 2:18:06.29 | 10:21/M | 2:F 35-39 |
| 51 | Kandace Sheets | 687 | 35 | F | Lynchburg VA | 2:19:27.38 | 10:27/M | 3:F 35-39 |
| 52 | Gemma Grove | 677 | 38 | F | Blacksburg VA | 2:20:21.30 | 10:31/M | 4:F 35-39 |
| 62 | Alice Stump | 633 | 36 | F | Roanoke VA | 2:29:23.27 | 11:11/M | 5:F 35-39 |
| 66 | Kelli Coleman | 680 | 35 | F | Lynchburg VA | 2:30:45.67 | 11:18/M | 6:F 35-39 |
| 83 | Tracy Proffitt | 635 | 39 | F | Lynchburg VA | 2:56:59.09 | 13:15/M | 7:F 35-39 |