October 29th, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 49 | Crystal Barksdale | 620 | 45 | F | Roanoke VA | 28:16.7 | 9:09/M | 1:F 45-49 |
| 50 | Shannon Honaker | 504 | 45 | F | Radford VA | 28:20.0 | 9:11/M | 2:F 45-49 |
| 67 | Jennifer Cleveland | 572 | 45 | F | Roanoke VA | 30:31.2 | 9:57/M | 3:F 45-49 |
| 94 | Lori Fields | 512 | 46 | F | Vinton VA | 33:28.5 | 10:54/M | 4:F 45-49 |
| 103 | Bridget Melvin | 507 | 46 | F | Buchanan VA | 34:59.6 | 11:21/M | 5:F 45-49 |
| 152 | Deanna Womack | 675 | 48 | F | Roanoke VA | 53:21.3 | 17:18/M | 6:F 45-49 |