November 20th, 2021
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 34 | Bobby Mountcastle | 53 | 41 | M | Roanoke VA | 1:37:31.9 | 7:27/M | 1:M 40-44 |
| 37 | Andrew Skidmore | 251 | 40 | M | Radford VA | 1:38:45.2 | 7:32/M | 2:M 40-44 |
| 47 | Ben Ziccardy | 64 | 41 | M | Roanoke VA | 1:42:06.6 | 7:48/M | 3:M 40-44 |
| 51 | James Smyth | 304 | 44 | M | Roanoke VA | 1:42:44.2 | 7:51/M | 4:M 40-44 |
| 61 | Daniel Cohen | 289 | 44 | M | Roanoke VA | 1:43:49.3 | 7:56/M | 5:M 40-44 |
| 108 | Matthew Churchill | 241 | 44 | M | Roanoke VA | 1:54:28.6 | 8:44/M | 6:M 40-44 |
| 115 | Tim Haggett | 182 | 41 | M | Roanoke VA | 1:56:20.0 | 8:53/M | 7:M 40-44 |
| 130 | David Cheresnowsky | 246 | 42 | M | Roanoke VA | 1:58:22.4 | 9:02/M | 8:M 40-44 |
| 139 | Bryce Anderson | 253 | 42 | M | Roanoke VA | 1:59:58.1 | 9:09/M | 9:M 40-44 |
| 148 | Nathan Brown | 294 | 43 | M | Roanoke VA | 2:01:10.9 | 9:15/M | 10:M 40-44 |
| 168 | Michael Henson | 7 | 40 | M | Roanoke VA | 2:05:35.9 | 9:35/M | 11:M 40-44 |
| 189 | Jaime Barcenas | 14 | 41 | M | Roanoke VA | 2:08:55.4 | 9:50/M | 12:M 40-44 |
| 225 | Matthew Osborne | 297 | 41 | M | Bumpass VA | 2:19:40.2 | 10:40/M | 13:M 40-44 |