May 7th, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 53 | Kari Decker | 607 | 44 | F | Roanoke VA | 2:20:56.22 | 10:33/M | 1:F 40-44 |
| 54 | Jessica Thornton | 650 | 43 | F | Blacksburg VA | 2:23:17.53 | 10:44/M | 2:F 40-44 |
| 58 | Nicole Sanford | 664 | 42 | F | Christiansburg VA | 2:25:30.30 | 10:54/M | 3:F 40-44 |
| 69 | Tara Pelletier | 647 | 41 | F | Columbus OH | 2:37:14.61 | 11:47/M | 4:F 40-44 |
| 72 | Denise Wilson | 675 | 40 | F | 2:41:18.04 | 12:05/M | 5:F 40-44 | |
| 78 | Adrien Monti | 627 | 43 | F | Roanoke VA | 2:45:19.42 | 12:23/M | 6:F 40-44 |
| 79 | Lauren Dogan | 691 | 41 | F | Vinton VA | 2:45:30.11 | 12:24/M | 7:F 40-44 |