February 26th, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 54 | Wendy Grider | 201 | 47 | F | Rocky Mount VA | 59:17.43 | 9:53/M | 1:F 45-49 |
| 64 | Kim Kitts | 283 | 49 | F | Christiansburg VA | 1:02:14.92 | 10:22/M | 2:F 45-49 |
| 74 | Ilona Parks | 209 | 45 | F | Roanoke VA | 1:05:26.63 | 10:54/M | 3:F 45-49 |
| 85 | Nicole Coleman | 289 | 46 | F | 1:10:12.42 | 11:42/M | 4:F 45-49 | |
| 98 | Jennifer White | 253 | 49 | F | Roanoke VA | 1:17:37.56 | 12:56/M | 5:F 45-49 |
| 102 | Shannon Honaker | 305 | 45 | F | Radford VA | 1:19:36.74 | 13:16/M | 6:F 45-49 |
| 111 | Melissa Ownby | 257 | 46 | F | Roanoke VA | 1:22:20.69 | 13:43/M | 7:F 45-49 |