September 17th, 2022
| Place | Name | Bib # | Age | Gender | Hometown | Time | Pace | Age Group Result |
|---|---|---|---|---|---|---|---|---|
| 27 | Lisa Preslar | 16 | 47 | F | 7:26:28.1 | 6:51/M | 1:F 40-49 | |
| 35 | Cherise Alva | 3 | 42 | F | 7:43:04.7 | 7:06/M | 2:F 40-49 | |
| 43 | Jana Elliott | 5 | 48 | F | Pilot Mountain NC | 8:12:08.9 | 7:33/M | 3:F 40-49 |
| 46 | Signe Ulsamer | 19 | 45 | F | 8:25:50.2 | 7:45/M | 4:F 40-49 | |
| 48 | Jennifer White | 20 | 49 | F | Roanoke VA | 8:30:08.9 | 7:49/M | 5:F 40-49 |
| 56 | Laura Jacobsen | 13 | 46 | F | Radford VA | 9:07:16.4 | 8:24/M | 6:F 40-49 |